PARD3 anticorps (AA 180-442)

N° du produit ABIN5704096

Cet anticorps Lapin Polyclonal détecte spécifiquement PARD3 dans WB, ELISA, IHC, FACS et IP. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour PARD3 anticorps (AA 180-442) (ABIN5704096)

Antigène: PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PARD3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunoprecipitation (IP)

Détail du produit anti-PARD3 anticorps

Épitope: AA 180-442

Fonction: PARD3 antibody

Immunogène:

Immunogen sequence: 180-442aa

Immunogen: Partitioning defective 3 homolog

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

MCF7 cells were subjected to SDS PAGE followed by western blot with FNab06146(PARD3 antibody) at dilution of 1:300

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur PARD3

Antigène: PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))

Autre désignation: PARD3

Sujet:

Synonyms: Partitioning defective 3 homolog (PAR-3, PARD-3)|Atypical PKC isotype-specific-interacting protein (ASIP)|CTCL tumor antigen se2-5|PAR3-alpha|PARD3|PAR3|PAR3A

Background: Adapter protein involved in asymmetrical cell division and cell polarization processes. Seems to play a central role in the formation of epithelial tight junctions. Targets the phosphatase PTEN to cell junctions. Involved in Schwann cell peripheral myelination(By similarity). Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons.PARD3 has three splice isoforms at 100 kDa, 150 kDa, and 180 kDa. This polyclonal antibody raised against C-terminal 281 amino acids of human PARD3 recognizes these three isoforms.

ID gène: 56288

UniProt: Q8TEW0

Pathways: Cell-Cell Junction Organization